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Tailoring to RB: tumour suppressor status and therapeutic response

The retinoblastoma tumour suppressor (RB) is a crucial regulator of cell-cycle progression that is invoked in response to a myriad of anti-mitogenic signals. It has been hypothesized that perturbations of the RB pathway confer a synonymous proliferative advantage to tumour cells; however, recent fin...

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Bibliografiska uppgifter
Huvudupphovsmän: Knudsen, Erik S., Knudsen, Karen E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914856/
https://ncbi.nlm.nih.gov/pubmed/19143056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2401
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