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Retinoblastoma Tumor Suppressor Status Is a Critical Determinant of Therapeutic Response in Prostate Cancer Cells

The retinoblastoma tumor suppressor protein (RB), a critical mediator of cell cycle progression, is functionally inactivated in the majority of human cancers, including prostatic adenocarcinoma. The importance of RB tumor suppressor function in this disease is evident because 25% to 50% of prostatic...

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Detalles Bibliográficos
Main Authors: Sharma, Ankur, Comstock, Clay E.S., Knudsen, Erik S., Cao, Khanh H., Hess-Wilson, Janet K., Morey, Lisa M., Barrera, Jason, Knudsen, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133940/
https://ncbi.nlm.nih.gov/pubmed/17616676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-4424
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