The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

Retinoblastoma (RB; encoded by RB1) is a tumor suppressor that is frequently disrupted in tumorigenesis and acts in multiple cell types to suppress cell cycle progression. The role of RB in tumor progression, however, is poorly defined. Here, we have identified a critical role for RB in protecting a...

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Detalhes bibliográficos
Main Authors: Sharma, Ankur, Yeow, Wen-Shuz, Ertel, Adam, Coleman, Ilsa, Clegg, Nigel, Thangavel, Chellappagounder, Morrissey, Colm, Zhang, Xiaotun, Comstock, Clay E.S., Witkiewicz, Agnieszka K., Gomella, Leonard, Knudsen, Erik S., Nelson, Peter S., Knudsen, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993601/
https://ncbi.nlm.nih.gov/pubmed/21099110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44239
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