The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

Retinoblastoma (RB; encoded by RB1) is a tumor suppressor that is frequently disrupted in tumorigenesis and acts in multiple cell types to suppress cell cycle progression. The role of RB in tumor progression, however, is poorly defined. Here, we have identified a critical role for RB in protecting a...

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Autors principals: Sharma, Ankur, Yeow, Wen-Shuz, Ertel, Adam, Coleman, Ilsa, Clegg, Nigel, Thangavel, Chellappagounder, Morrissey, Colm, Zhang, Xiaotun, Comstock, Clay E.S., Witkiewicz, Agnieszka K., Gomella, Leonard, Knudsen, Erik S., Nelson, Peter S., Knudsen, Karen E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993601/
https://ncbi.nlm.nih.gov/pubmed/21099110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44239
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