The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

Retinoblastoma (RB; encoded by RB1) is a tumor suppressor that is frequently disrupted in tumorigenesis and acts in multiple cell types to suppress cell cycle progression. The role of RB in tumor progression, however, is poorly defined. Here, we have identified a critical role for RB in protecting a...

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Main Authors: Sharma, Ankur, Yeow, Wen-Shuz, Ertel, Adam, Coleman, Ilsa, Clegg, Nigel, Thangavel, Chellappagounder, Morrissey, Colm, Zhang, Xiaotun, Comstock, Clay E.S., Witkiewicz, Agnieszka K., Gomella, Leonard, Knudsen, Erik S., Nelson, Peter S., Knudsen, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993601/
https://ncbi.nlm.nih.gov/pubmed/21099110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44239
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