Unique Bisphenol A Transcriptome in Prostate Cancer: Novel Effects on ERβ Expression That Correspond to Androgen Receptor Mutation Status

BACKGROUND: Prostatic adenocarcinomas are dependent on androgen receptor (AR) activity for growth and progression, and therapy for disseminated disease depends on ablation of AR activity. Recurrent tumors ultimately arise wherein AR has been re-activated. One mechanism of AR restoration is via somat...

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Autors principals: Hess-Wilson, Janet K., Webb, Siobhan L., Daly, Hannah K., Leung, Yuet-Kin, Boldison, Joanne, Comstock, Clay E.S., Sartor, Maureen A., Ho, Shuk-Mei, Knudsen, Karen E.
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2007
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072856/
https://ncbi.nlm.nih.gov/pubmed/18007998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.10283
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