Unique Bisphenol A Transcriptome in Prostate Cancer: Novel Effects on ERβ Expression That Correspond to Androgen Receptor Mutation Status

BACKGROUND: Prostatic adenocarcinomas are dependent on androgen receptor (AR) activity for growth and progression, and therapy for disseminated disease depends on ablation of AR activity. Recurrent tumors ultimately arise wherein AR has been re-activated. One mechanism of AR restoration is via somat...

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Autori principali: Hess-Wilson, Janet K., Webb, Siobhan L., Daly, Hannah K., Leung, Yuet-Kin, Boldison, Joanne, Comstock, Clay E.S., Sartor, Maureen A., Ho, Shuk-Mei, Knudsen, Karen E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Institute of Environmental Health Sciences 2007
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072856/
https://ncbi.nlm.nih.gov/pubmed/18007998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.10283
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