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The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer
The retinoblastoma tumor suppressor (RB) protein is functionally inactivated in the majority of human cancers and is aberrant in one-third of all breast cancers. RB regulates G(1)/S-phase cell-cycle progression and is a critical mediator of antiproliferative signaling. Here the specific impact of RB...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1679964/ https://ncbi.nlm.nih.gov/pubmed/17160137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28803 |
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