RB-pathway disruption in breast cancer: Differential association with disease subtypes, disease-specific prognosis and therapeutic response

In breast cancer, inactivation of the RB tumor suppressor gene is believed to occur via multiple mechanisms to facilitate tumorigenesis. However, the prognostic and predictive value of RB status in disease-specific clinical outcomes has remained uncertain. We investigated RB pathway deregulation in...

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Autores principales: Ertel, Adam, Dean, Jeffry L, Rui, Hallgeir, Liu, Chengbao, Witkiewicz, Agnes K, Knudsen, Karen E, Knudsen, Erik S
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055199/
https://ncbi.nlm.nih.gov/pubmed/20948315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13454
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