Structure-based immunogen design — leading the way to the new age of precision vaccines

por Sesterhenn, Fabian, Bonet, Jaume, Correia, Bruno E
Publicado en Curr Opin Struct Biol (2018)

Mapping the Protein Interaction Landscape for Fully Functionalized Small-Molecule Probes in Human Cells

por Kambe, Tohru, Correia, Bruno E., Niphakis, Micah J., Cravatt, Benjamin F.
Publicado 2014

Integrating gene synthesis and microfluidic protein analysis for rapid protein engineering

por Blackburn, Matthew C., Petrova, Ekaterina, Correia, Bruno E., Maerkl, Sebastian J.
Publicado en Nucleic Acids Res (2016)

rstoolbox - a Python library for large-scale analysis of computational protein design data and structural bioinformatics

por Bonet, Jaume, Harteveld, Zander, Sesterhenn, Fabian, Scheck, Andreas, Correia, Bruno E.
Publicado en BMC Bioinformatics (2019)

A structural model of an amyloid protofilament of Transthyretin

por Correia, Bruno E., Loureiro-Ferreira, Nuno, Rodrigues, J. Rui, Brito, Rui M.M.
Publicado 2006

High-resolution structure prediction of a circular permutation loop

por Correia, Bruno E, Holmes, Margaret A, Huang, Po-Ssu, Strong, Roland K, Schief, William R
Publicado 2011

Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity

por Frangolho, Ana, Correia, Bruno E., Vaz, Daniela C., Almeida, Zaida L., Brito, Rui M. M.
Publicado en Molecules (2020)

Reversion of Somatic Mutations of the Respiratory Syncytial Virus-Specific Human Monoclonal Antibody Fab19 Reveal a Direct Relationship Between Association Rate and Neutralizing Po...

por Bates, John T., Keefer, Christopher J., Utley, Thomas J., Correia, Bruno E., Schief, William R., Crowe, James E.
Publicado 2013

Global profiling of lysine reactivity and ligandability in the human proteome

por Hacker, Stephan M., Backus, Keriann M., Lazear, Michael R., Forli, Stefano, Correia, Bruno E., Cravatt, Benjamin F.
Publicado en Nat Chem (2017)

Design and Characterization of Epitope-Scaffold Immunogens that Present the Motavizumab Epitope from Respiratory Syncytial Virus

por McLellan, Jason S., Correia, Bruno E., Chen, Man, Yang, Yongping, Graham, Barney S., Schief, William R., Kwong, Peter D.
Publicado 2011

Chemoproteomic profiling and discovery of protein electrophiles in human cells

por Matthews, Megan L, He, Lin, Horning, Benjamin D, Olson, Erika J, Correia, Bruno E, Yates, John R, Dawson, Philip E, Cravatt, Benjamin F
Publicado en Nat Chem (2016)

Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein

por Hoffmann, Mareike D, Mathony, Jan, Upmeier zu Belzen, Julius, Harteveld, Zander, Aschenbrenner, Sabine, Stengl, Christina, Grimm, Dirk, Correia, Bruno E, Eils, Roland, Niopek, Dominik
Publicado en Nucleic Acids Res (2020)

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant

por Bouvignies, Guillaume, Vallurupalli, Pramodh, Hansen, D. Flemming, Correia, Bruno E., Lange, Oliver, Bah, Alaji, Vernon, Robert M., Dahlquist, Frederick W., Baker, David, Kay, Lewis E.
Publicado 2011

Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A

por Geiger, Kristina M., Guignard, Daniel, Yang, Che, Bikorimana, Jean-Pierre, Correia, Bruno E., Houard, Sophie, Mkindi, Catherine, Daubenberger, Claudia A., Spertini, François, Corradin, Giampietro, Audran, Régine
Publicado en Front Immunol (2020)

A global map of lipid-binding proteins and their ligandability in cells

por Niphakis, Micah J., Lum, Kenneth M., Cognetta, Armand B., Correia, Bruno E., Ichu, Taka-Aki, Olucha, Jose, Brown, Steven J., Kundu, Soumajit, Piscitelli, Fabiana, Rosen, Hugh, Cravatt, Benjamin F.
Publicado en Cell (2015)

Rosetta FunFolDes – A general framework for the computational design of functional proteins

por Bonet, Jaume, Wehrle, Sarah, Schriever, Karen, Yang, Che, Billet, Anne, Sesterhenn, Fabian, Scheck, Andreas, Sverrisson, Freyr, Veselkova, Barbora, Vollers, Sabrina, Lourman, Roxanne, Villard, Mélanie, Rosset, Stéphane, Krey, Thomas, Correia, Bruno E.
Publicado en PLoS Comput Biol (2018)

Ligand and Target Discovery by Fragment-Based Screening in Human Cells

por Parker, Christopher G., Galmozzi, Andrea, Wang, Yujia J., Correia, Bruno E., Sasaki, Kenji, Joslyn, Christopher M., Kim, Arthur S., Cavallaro, Cullen L., Lawrence, Michael, Johnson, Stephen R., Narvaiza, Iñigo, Saez, Enrique, Cravatt, Benjamin F.
Publicado en Cell (2017)

Proteome-wide covalent ligand discovery in native biological systems

por Backus, Keriann M., Correia, Bruno E., Lum, Kenneth M., Forli, Stefano, Horning, Benjamin D., González-Páez, Gonzalo E., Chatterjee, Sandip, Lanning, Bryan R., Teijaro, John R., Olson, Arthur J., Wolan, Dennis W., Cravatt, Benjamin F.
Publicado en Nature (2016)

A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells

por Procko, Erik, Berguig, Geoffrey Y., Shen, Betty W., Song, Yifan, Frayo, Shani, Convertine, Anthony J., Margineantu, Daciana, Booth, Garrett, Correia, Bruno E., Cheng, Yuanhua, Schief, William R., Hockenbery, David M., Press, Oliver W., Stoddard, Barry L., Stayton, Patrick S., Baker, David
Publicado 2014

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

por Sesterhenn, Fabian, Galloux, Marie, Vollers, Sabrina S., Csepregi, Lucia, Yang, Che, Descamps, Delphyne, Bonet, Jaume, Friedensohn, Simon, Gainza, Pablo, Corthésy, Patricia, Chen, Man, Rosset, Stéphane, Rameix-Welti, Marie-Anne, Éléouët, Jean-François, Reddy, Sai T., Graham, Barney S., Riffault, Sabine, Correia, Bruno E.
Publicado en PLoS Biol (2019)