Advances in targeting the folate receptor in the treatment/imaging of cancers

por Fernández, Marcos, Javaid, Faiza, Chudasama, Vijay
Publicado en Chem Sci (2017)

Formation of Synthetically Versatile 2-Aminobenzophenones from Readily Accessed Acyl Hydrazides

por Ahmed, Nehaal, Shamsabadi, André, Chudasama, Vijay
Publicado en ACS Omega (2019)

Antibody fragments as nanoparticle targeting ligands: a step in the right direction

por Richards, Daniel A., Maruani, Antoine, Chudasama, Vijay
Publicado en Chem Sci (2017)

Cysteine-to-lysine transfer antibody fragment conjugation

por Forte, Nafsika, Benni, Irene, Karu, Kersti, Chudasama, Vijay, Baker, James R.
Publicado en Chem Sci (2019)

Tyrosine bioconjugation – an emergent alternative

por Szijj, Peter A., Kostadinova, Kristina A., Spears, Richard J., Chudasama, Vijay
Publicado en Org Biomol Chem (2020)

Next-generation disulfide stapling: reduction and functional re-bridging all in one

por Lee, Maximillian T. W., Maruani, Antoine, Baker, James R., Caddick, Stephen, Chudasama, Vijay
Publicado en Chem Sci (2016)

A novel synthetic chemistry approach to linkage-specific ubiquitin conjugation

por Morgan, Rachel E., Chudasama, Vijay, Moody, Paul, Smith, Mark E. B., Caddick, Stephen
Publicado en Org Biomol Chem (2015)

Motional timescale predictions by molecular dynamics simulations: Case study using proline and hydroxyproline sidechain dynamics

por Aliev, Abil E, Kulke, Martin, Khaneja, Harmeet S, Chudasama, Vijay, Sheppard, Tom D, Lanigan, Rachel M
Publicado en Proteins (2014)

A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy

por Maruani, Antoine, Smith, Mark E.B., Miranda, Enrique, Chester, Kerry A., Chudasama, Vijay, Caddick, Stephen
Publicado en Nat Commun (2015)

Enabling the controlled assembly of antibody conjugates with a loading of two modules without antibody engineering

por Lee, Maximillian T. W., Maruani, Antoine, Richards, Daniel A., Baker, James R., Caddick, Stephen, Chudasama, Vijay
Publicado en Chem Sci (2017)

A novel approach to the site-selective dual labelling of a protein via chemoselective cysteine modification

por Nathani, Ramiz I., Moody, Paul, Chudasama, Vijay, Smith, Mark E. B., Fitzmaurice, Richard J., Caddick, Stephen
Publicado 2013

A rapid, site-selective and efficient route to the dual modification of DARPins

por Moody, Paul, Chudasama, Vijay, Nathani, Ramiz I., Maruani, Antoine, Martin, Stephen, Smith, Mark E. B., Caddick, Stephen
Publicado 2014

Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4

por Maneiro, María, Forte, Nafsika, Shchepinova, Maria M., Kounde, Cyrille S., Chudasama, Vijay, Baker, James Richard, Tate, Edward W.
Publicado en ACS Chem Biol (2020)

Bromomaleimide-Linked Bioconjugates Are Cleavable in Mammalian Cells

por Moody, Paul, Smith, Mark E B, Ryan, Chris P, Chudasama, Vijay, Baker, James R, Molloy, Justin, Caddick, Stephen
Publicado 2012

Bromopyridazinedione-mediated protein and peptide bioconjugation

por Chudasama, Vijay, Smith, Mark E. B., Schumacher, Felix F., Papaioannou, Danai, Waksman, Gabriel, Baker, James R., Caddick, Stephen
Publicado 2011

Optical control of trimeric P2X receptors and acid-sensing ion channels

por Browne, Liam E., Nunes, João P. M., Sim, Joan A., Chudasama, Vijay, Bragg, Laricia, Caddick, Stephen, Alan North, R.
Publicado 2014

Highly homogeneous antibody modification through optimisation of the synthesis and conjugation of functionalised dibromopyridazinediones

por Bahou, Calise, Richards, Daniel A., Maruani, Antoine, Love, Elizabeth A., Javaid, Faiza, Caddick, Stephen, Baker, James R., Chudasama, Vijay
Publicado en Org Biomol Chem (2018)

Functionalised thermally induced phase separation (TIPS) microparticles enabled for “click” chemistry

por Nogueira, João C. F., Paliashvili, Ketevan, Bradford, Alexandra, Di Maggio, Francesco, Richards, Daniel A., Day, Richard M., Chudasama, Vijay
Publicado en Org Biomol Chem (2020)

One-pot thiol–amine bioconjugation to maleimides: simultaneous stabilisation and dual functionalisation

por Wall, Archie, Wills, Alfie G., Forte, Nafsika, Bahou, Calise, Bonin, Lisa, Nicholls, Karl, Ma, Michelle T., Chudasama, Vijay, Baker, James R.
Publicado en Chem Sci (2020)

Forming next-generation antibody–nanoparticle conjugates through the oriented installation of non-engineered antibody fragments

por Greene, Michelle K., Richards, Daniel A., Nogueira, João C. F., Campbell, Katrina, Smyth, Peter, Fernández, Marcos, Scott, Christopher J., Chudasama, Vijay
Publicado en Chem Sci (2017)