Bromopyridazinedione-mediated protein and peptide bioconjugation

Por Chudasama, Vijay, Smith, Mark E. B., Schumacher, Felix F., Papaioannou, Danai, Waksman, Gabriel, Baker, James R., Caddick, Stephen
Publicado em 2011

In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation

Por Schumacher, Felix F., Nobles, Muriel, Ryan, Chris P., Smith, Mark E. B., Tinker, Andrew, Caddick, Stephen, Baker, James R.
Publicado em 2011

Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

Por Smith, Mark E. B., Schumacher, Felix F., Ryan, Chris P., Tedaldi, Lauren M., Papaioannou, Danai, Waksman, Gabriel, Caddick, Stephen, Baker, James R.
Publicado em 2010

Zinc Binding to the Tyr402 and His402 Allotypes of Complement Factor H: Possible Implications for Age-Related Macular Degeneration

Por Nan, Ruodan, Farabella, Irene, Schumacher, Felix F., Miller, Ami, Gor, Jayesh, Martin, Andrew C.R., Jones, David T., Lengyel, Imre, Perkins, Stephen J.
Publicado em 2011

Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis

Por Ryan, Chris P., Smith, Mark E. B., Schumacher, Felix F., Grohmann, Dina, Papaioannou, Danai, Waksman, Gabriel, Werner, Finn, Baker, James R., Caddick, Stephen
Publicado em 2011

Acid-cleavable thiomaleamic acid linker for homogeneous antibody–drug conjugation

Por Castañeda, Lourdes, Maruani, Antoine, Schumacher, Felix F., Miranda, Enrique, Chudasama, Vijay, Chester, Kerry A., Baker, James R., Smith, Mark E. B., Caddick, Stephen
Publicado em 2013

Next generation maleimides enable the controlled assembly of antibody–drug conjugates via native disulfide bond bridging

Por Schumacher, Felix F., Nunes, João P. M., Maruani, Antoine, Chudasama, Vijay, Smith, Mark E. B., Chester, Kerry A., Baker, James R., Caddick, Stephen
Publicado em 2014

Homogeneous antibody fragment conjugation by disulfide bridging introduces ‘spinostics'

Por Schumacher, Felix F., Sanchania, Vishal A., Tolner, Berend, Wright, Zoë V. F., Ryan, Chris P., Smith, Mark E. B., Ward, John M., Caddick, Stephen, Kay, Christopher W. M., Aeppli, Gabriel, Chester, Kerry A., Baker, James R.
Publicado em 2013