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In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation
The introduction of non-natural entities into proteins by chemical modification has numerous applications in fundamental biological science and for the development and manipulation of peptide and protein therapeutics. The reduction of native disulfide bonds provides a convenient method to access two...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039925/ https://ncbi.nlm.nih.gov/pubmed/21271715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc1004685 |
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