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Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

[Image: see text] The maleimide motif is widely used for the selective chemical modification of cysteine residues in proteins. Despite widespread utilization, there are some potential limitations, including the irreversible nature of the reaction and, hence, the modification and the number of attach...

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Bibliografische gegevens
Hoofdauteurs: Smith, Mark E. B., Schumacher, Felix F., Ryan, Chris P., Tedaldi, Lauren M., Papaioannou, Danai, Waksman, Gabriel, Caddick, Stephen, Baker, James R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2010
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842020/
https://ncbi.nlm.nih.gov/pubmed/20092331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908610s
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