Protein Modification, Bioconjugation, and Disulfide Bridging Using Bromomaleimides

[Image: see text] The maleimide motif is widely used for the selective chemical modification of cysteine residues in proteins. Despite widespread utilization, there are some potential limitations, including the irreversible nature of the reaction and, hence, the modification and the number of attach...

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Autori principali: Smith, Mark E. B., Schumacher, Felix F., Ryan, Chris P., Tedaldi, Lauren M., Papaioannou, Danai, Waksman, Gabriel, Caddick, Stephen, Baker, James R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2010
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842020/
https://ncbi.nlm.nih.gov/pubmed/20092331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908610s
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