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Homogeneous Bispecifics by Disulfide Bridging
[Image: see text] We report on a chemical platform to generate site-specific, homogeneous, antibody–antibody conjugates by targeting and bridging disulfide bonds. A bispecific antibody construct was produced in good yield through simple reduction and bridging of antibody fragment disulfide bonds, us...
Tallennettuna:
| Julkaisussa: | Bioconjug Chem |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American
Chemical Society
2014
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4458859/ https://ncbi.nlm.nih.gov/pubmed/25033024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc5002467 |
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