Chargement en cours...

Highly homogeneous antibody modification through optimisation of the synthesis and conjugation of functionalised dibromopyridazinediones

Due to their exquisite cysteine-selectivity, excellent stability, and ability to functionally rebridge disulfide bonds, dibromopyridazinediones are emerging as an exciting new class of bioconjugation reagents, particularly in the field of antibody conjugation. Despite this, relatively little work ha...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Org Biomol Chem
Auteurs principaux: Bahou, Calise, Richards, Daniel A., Maruani, Antoine, Love, Elizabeth A., Javaid, Faiza, Caddick, Stephen, Baker, James R., Chudasama, Vijay
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058253/
https://ncbi.nlm.nih.gov/pubmed/29405223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob03138f
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!