Forming next-generation antibody–nanoparticle conjugates through the oriented installation of non-engineered antibody fragments

Por Greene, Michelle K., Richards, Daniel A., Nogueira, João C. F., Campbell, Katrina, Smyth, Peter, Fernández, Marcos, Scott, Christopher J., Chudasama, Vijay
Publicado no Chem Sci (2017)

Oriented attachment of V(NAR) proteins, via site-selective modification, on PLGA–PEG nanoparticles enhances nanoconjugate performance

Por Nogueira, João C. F., Greene, Michelle K., Richards, Daniel A., Furby, Alexander O., Steven, John, Porter, Andrew, Barelle, Caroline, Scott, Christopher J., Chudasama, Vijay
Publicado no Chem Commun (Camb) (2019)

Repurposing of Cetuximab in antibody-directed chemotherapy-loaded nanoparticles in EGFR therapy-resistant pancreatic tumours

Por McDaid, William J., Greene, Michelle K., Johnston, Michael C., Pollheimer, Ellen, Smyth, Peter, McLaughlin, Kirsty, Van Schaeybroeck, Sandra, Straubinger, Robert M., Longley, Daniel B., Scott, Christopher J.
Publicado no Nanoscale (2019)

USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor

Por Jaworski, Jakub, de la Vega, Michelle, Fletcher, Sarah J., McFarlane, Cheryl, Greene, Michelle K., Smyth, Andrew W., Van Schaeybroeck, Sandra, Johnston, James A., Scott, Christopher J., Rappoport, Joshua Z., Burrows, James F.
Publicado em 2014

Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer

Por Greene, Michelle K., Chen, Ting, Robinson, Eifion, Straubinger, Ninfa L., Minx, Charlene, Chan, Darren K. W., Wang, Jun, Burrows, James F., Van Schaeybroeck, Sandra, Baker, James R., Caddick, Stephen, Longley, Daniel B., Mager, Donald E., Straubinger, Robert M., Chudasama, Vijay, Scott, Christopher J.
Publicado no Br J Cancer (2020)