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Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4
[Image: see text] Targeting protein degradation with Proteolysis-Targeting Chimeras (PROTACs) is an area of great current interest in drug discovery. Nevertheless, although the high effectiveness of PROTACs against a wide variety of targets has been established, most degraders reported to date displ...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Chem Biol |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical
Society
2020
|
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7309268/ https://ncbi.nlm.nih.gov/pubmed/32338867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00285 |
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