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TF-PROTACs Enable Targeted Degradation of Transcription Factors
Transcription factors (TFs) represent a major class of therapeutic targets for the treatment of human diseases including cancer. Although the biological functions and even crystal structures of many TFs have been clearly elucidated, there is still no viable approach to target the majority of TFs, th...
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| Veröffentlicht in: | J Am Chem Soc |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8225582/ https://ncbi.nlm.nih.gov/pubmed/34100597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.1c03852 |
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