Caricamento...
The therapeutic effect of the BRD4-degrading PROTAC A1874 in human colon cancer cells
A1874 is a novel BRD4-degrading proteolysis targeting chimera (PROTAC). In primary colon cancer cells and established HCT116 cells, A1874 potently inhibited cell viability, proliferation, cell cycle progression, as well as cell migration and invasion. The BRD4-degrading PROTAC was able to induce cas...
Salvato in:
| Pubblicato in: | Cell Death Dis |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519683/ https://ncbi.nlm.nih.gov/pubmed/32978368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03015-6 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|