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A novel synthetic chemistry approach to linkage-specific ubiquitin conjugation

Ubiquitination is of great importance as the post-translational modification of proteins with ubiquitin, or ubiquitin chains, facilitates a number of vital cellular processes. Herein we present a facile method of preparing various ubiquitin conjugates under mild conditions using michael acceptors ba...

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Bibliografski detalji
Izdano u:Org Biomol Chem
Glavni autori: Morgan, Rachel E., Chudasama, Vijay, Moody, Paul, Smith, Mark E. B., Caddick, Stephen
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372856/
https://ncbi.nlm.nih.gov/pubmed/25736233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob00130g
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