Depleting tumor-NQO1 Potentiates Anoikis and Inhibits Growth of NSCLC

بواسطة Madajewski, Brian, Boatman, Michael A., Chakrabarti, Gaurab, Boothman, David A., Bey, Erik A.
الحاوية / القاعدة Mol Cancer Res (2015)

β-Lapachone-containing PEG-PLA Polymer Micelles as Novel Nanotherapeutics against NQO1-Overexpressing Tumor Cells

بواسطة Blanco, Elvin, Bey, Erik A., Dong, Ying, Weinberg, Brent D., Sutton, Damon M., Boothman, David A., Gao, Jinming
منشور في 2007

Superparamagnetic Iron Oxide Nanoparticles: Amplifying ROS Stress to Improve Anticancer Drug Efficacy

بواسطة Huang, Gang, Chen, Huabing, Dong, Ying, Luo, Xiuquan, Yu, Haijun, Moore, Zachary, Bey, Erik A., Boothman, David A., Gao, Jinming
منشور في 2013

Hemoglobin-Based Oxygen Carrier Mitigates Transfusion-Mediated Pancreas Cancer Progression

بواسطة Lo, Karen K., Bey, Erik A., Patra, Biswantha, Benson, Douglas D., Boothman, David A., Silliman, Christopher C., Barnett, Carlton C.
منشور في 2013

Review of Poly (ADP-ribose) Polymerase (PARP) Mechanisms of Action and Rationale for Targeting in Cancer and Other Diseases

بواسطة Morales, Julio C., Li, Longshan, Fattah, Farjana J., Dong, Ying, Bey, Erik A., Patel, Malina, Gao, Jinming, Boothman, David A.
الحاوية / القاعدة Crit Rev Eukaryot Gene Expr (2014)

Dual PI3K/mTOR blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations

بواسطة Konstantinidou, Georgia, Bey, Erik A., Rabellino, Andrea, Schuster, Katja, Maira, Michael S., Gazdar, Adi F., Amici, Augusto, Boothman, David A., Scaglioni, Pier Paolo
منشور في 2009

Intratumoral Delivery of β-Lapachone via Polymer Implants for Prostate Cancer Therapy

بواسطة Dong, Ying, Chin, Shook-Fong, Blanco, Elvin, Bey, Erik A, Kabbani, Wareef, Xie, Xian-Jin, Bornmann, William G., Boothman, David A., Gao, Jinming
منشور في 2009

Prostate cancer radiosensitization through PARP-1 hyperactivation

بواسطة Dong, Ying, Bey, Erik A., Li, Long-Shan, Kabbani, Wareef, Yan, Jingsheng, Xie, Xian-Jin, Hsieh, Jer-Tsong, Gao, Jinming, Boothman, David A.
منشور في 2010

In vivo Off-Resonance Saturation Magnetic Resonance Imaging of α(v)β(3)-Targeted Superparamagnetic Nanoparticles

بواسطة Khemtong, Chalermchai, Kessinger, Chase W., Ren, Jimin, Bey, Erik A., Yang, Su-Geun, Guthi, Jagadeesh Setti, Boothman, David A., Sherry, A. Dean, Gao, Jinming
منشور في 2009

An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone

بواسطة Bey, Erik A., Bentle, Melissa S., Reinicke, Kathryn E., Dong, Ying, Yang, Chin-Rang, Girard, Luc, Minna, John D., Bornmann, William G., Gao, Jinming, Boothman, David A.
منشور في 2007

NQO1-dependent, tumor-selective radiosensitization of non-small cell lung cancers

بواسطة Motea, Edward A., Huang, Xiumei, Singh, Naveen, Kilgore, Jessica, Williams, Noelle, Xie, Xian-Jin, Gerber, David E., Beg, Muhammad Shaalan, Bey, Erik A., Boothman, David A.
الحاوية / القاعدة Clin Cancer Res (2019)

Targeting Base Excision Repair in Cancer: NQO1-Bioactivatable Drugs Improve Tumor Selectivity and Reduce Treatment Toxicity Through Radiosensitization of Human Cancer

بواسطة Starcher, Colton L., Pay, S. Louise, Singh, Naveen, Yeh, I-Ju, Bhandare, Snehal B., Su, Xiaolin, Huang, Xiumei, Bey, Erik A., Motea, Edward A., Boothman, David A.
الحاوية / القاعدة Front Oncol (2020)

β-Lapachone Micellar Nanotherapeutics for Non-Small Cell Lung Cancer Therapy

بواسطة Blanco, Elvin, Bey, Erik A., Khemtong, Chalermchai, Yang, Su-Geun, Setti-Guthi, Jagadeesh, Chen, Huabing, Kessinger, Chase W., Carnevale, Kevin A., Bornmann, William G., Boothman, David A., Gao, Jinming
منشور في 2010

Modulating Endogenous NQO1 Levels Identifies Key Regulatory Mechanisms of Action of β-Lapachone for Pancreatic Cancer Therapy

بواسطة Li, Long Shan, Bey, Erik A., Dong, Ying, Meng, Jieru, Patra, Biswanath, Yan, Jingsheng, Xie, Xian-Jin, Brekken, Rolf A., Barnett, Carlton C., Bornmann, William G., Gao, Jinming, Boothman, David A.
الحاوية / القاعدة Clin Cancer Res (2011)

An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis

بواسطة Huang, Xiumei, Dong, Ying, Bey, Erik A., Kilgore, Jessica A., Bair, Joseph S., Li, Long-Shan, Patel, Malina, Parkinson, Elizabeth I., Wang, Yiguang, Williams, Noelle S., Gao, Jinming, Hergenrother, Paul J., Boothman, David A.
الحاوية / القاعدة Cancer Res (2012)

Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers

بواسطة Bey, Erik A., Reinicke, Kathryn E., Srougi, Melissa C., Varnes, Marie, Anderson, Vernon, Pink, John J., Li, Long Shan, Patel, Malina, Cao, Lifen, Moore, Zachary, Rommel, Amy, Boatman, Michael, Lewis, Cheryl, Euhus, David M., Bornmann, William G., Buchsbaum, Donald J., Spitz, Douglas R., Gao, Jinming, Boothman, David A.
منشور في 2013

Tumor-Selective, Futile Redox Cycle-Induced Bystander Effects Elicited by NQO1 Bioactivatable Radiosensitizing Drugs in Triple-Negative Breast Cancers

بواسطة Cao, Lifen, Li, Long Shan, Spruell, Christopher, Xiao, Ling, Chakrabarti, Gaurab, Bey, Erik A., Reinicke, Kathryn E., Srougi, Melissa C., Moore, Zachary, Dong, Ying, Vo, Peggy, Kabbani, Wareef, Yang, Chin-Rang, Wang, Xiaoyu, Fattah, Farjana, Morales, Julio C., Motea, Edward A., Bornmann, William G., Yordy, John S., Boothman, David A.
منشور في 2014

Y Chromosome LncRNA are involved in Radiation Response of Male Non-Small Cell Lung Cancer Cells

بواسطة Brownmiller, Tayvia, Juric, Jamie A., Ivey, Abby D., Harvey, Brandon M., Westemeier, Emily S., Winters, Michael T., Stevens, Alyson M., Stanley, Alana N., Hayes, Karen E., Sprowls, Samuel A., Ammer, Amanda S. Gatesman, Walker, Mackenzee, Bey, Erik A., Wu, Xiaoliang, Lim, Zuan-Fu, Zhu, Lin, Wen, Sijin, Hu, Gangqing, Ma, Patrick C., Martinez, Ivan
الحاوية / القاعدة Cancer Res (2020)

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase (PARP) Inhibitors

بواسطة Huang, Xiumei, Motea, Edward A., Moore, Zachary R., Yao, Jun, Dong, Ying, Chakrabarti, Gaurab, Kilgore, Jessica A., Silvers, Molly A., Patidar, Praveen L., Cholka, Agnieszka, Fattah, Farjana, Cha, Yoonjeong, Anderson, Glenda G., Kusko, Rebecca, Peyton, Michael, Yan, Jingsheng, Xie, Xian-Jin, Sarode, Venetia, Williams, Noelle S., Minna, John D., Beg, Muhammad, Gerber, David E., Bey, Erik A., Boothman, David A.
الحاوية / القاعدة Cancer Cell (2016)