2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions

af Basse, Marie-Jeanne, Betzi, Stéphane, Morelli, Xavier, Roche, Philippe
Udgivet i Database (Oxford) (2016)

The Fungal Product Terreic Acid is a Covalent Inhibitor of the Bacterial Cell Wall Biosynthetic Enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA)

af Han, Huijong, Yang, Yan, Olesen, Sanne H., Becker, Andreas, Betzi, Stephane, Schönbrunn, Ernst
Udgivet 2010

Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining

af Normanno, Davide, Négrel, Aurélie, de Melo, Abinadabe J, Betzi, Stéphane, Meek, Katheryn, Modesti, Mauro
Udgivet i eLife (2017)

A novel approach to the discovery of small molecule ligands of CDK2

af Martin, Mathew P., Alam, Riazul, Betzi, Stephane, Ingles, Donna J., Zhu, Jin-Yi, Schönbrunn, Ernst
Udgivet 2012

Protein–protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein

af Betzi, Stéphane, Restouin, Audrey, Opi, Sandrine, Arold, Stefan T., Parrot, Isabelle, Guerlesquin, Françoise, Morelli, Xavier, Collette, Yves
Udgivet 2007

Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA)

af Zhu, Jin-Yi, Yang, Yan, Han, Huijong, Betzi, Stephane, Olesen, Sanne H., Marsilio, Frank, Schönbrunn, Ernst
Udgivet 2012

Crystal Structure of the Vaccinia Virus DNA Polymerase Holoenzyme Subunit D4 in Complex with the A20 N-Terminal Domain

af Contesto-Richefeu, Céline, Tarbouriech, Nicolas, Brazzolotto, Xavier, Betzi, Stéphane, Morelli, Xavier, Burmeister, Wim P., Iseni, Frédéric
Udgivet 2014

2P2Idb: a structural database dedicated to orthosteric modulation of protein–protein interactions

af Basse, Marie Jeanne, Betzi, Stéphane, Bourgeas, Raphaël, Bouzidi, Sofia, Chetrit, Bernard, Hamon, Véronique, Morelli, Xavier, Roche, Philippe
Udgivet 2013

Discovery of a potential allosteric ligand binding site in CDK2

af Betzi, Stephane, Alam, Riazul, Martin, Mathew, Lubbers, Donna J., Han, Huijong, Jakkaraj, Sudhakar R., Georg, Gunda I., Schönbrunn, Ernst
Udgivet 2011

Stability of the Human Hsp90-p50(Cdc37) Chaperone Complex against Nucleotides and Hsp90 Inhibitors, and the Influence of Phosphorylation by Casein Kinase 2

af Olesen, Sanne H., Ingles, Donna J., Zhu, Jin-Yi, Martin, Mathew P., Betzi, Stephane, Georg, Gunda I., Tash, Joseph S., Schönbrunn, Ernst
Udgivet i Molecules (2015)

Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer

af Birol, Melissa, Enchev, Radoslav Ivanov, Padilla, André, Stengel, Florian, Aebersold, Ruedi, Betzi, Stéphane, Yang, Yinshan, Hoh, François, Peter, Matthias, Dumas, Christian, Echalier, Aude
Udgivet 2014

The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane

af Berndt, Norbert, Yang, Hua, Trinczek, Bernhard, Betzi, Stéphane, Zhang, Ziming, Wu, Bainan, Lawrence, Nicholas J., Pellecchia, Maurizio, Schönbrunn, Ernst, Cheng, Jin Q., Sebti, Saïd M.
Udgivet 2010

Molecular Mapping of the RNA Cap 2′-O-Methyltransferase Activation Interface between Severe Acute Respiratory Syndrome Coronavirus nsp10 and nsp16

af Lugari, Adrien, Betzi, Stephane, Decroly, Etienne, Bonnaud, Emmanuel, Hermant, Aurélie, Guillemot, Jean-Claude, Debarnot, Claire, Borg, Jean-Paul, Bouvet, Mickaël, Canard, Bruno, Morelli, Xavier, Lécine, Patrick
Udgivet 2010

Structural recognition mechanisms between human Src Homology domain 3 (SH3) and ALG-2-Interacting protein X (Alix)

af Shi, Xiaoli, Betzi, Stephane, Lugari, Adrien, Opi, Sandrine, Restouin, Audrey, Parrot, Isabelle, Martinez, Jean, Zimmermann, Pascale, Lecine, Patrick, Huang, Mingdong, Arold, Stefan T., Collette, Yves, Morelli, Xavier
Udgivet 2012

In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor

af Ariey‐Bonnet, Jeremy, Carrasco, Kendall, Le Grand, Marion, Hoffer, Laurent, Betzi, Stéphane, Feracci, Mikael, Tsvetkov, Philipp, Devred, Francois, Collette, Yves, Morelli, Xavier, Ballester, Pedro, Pasquier, Eddy
Udgivet i Mol Oncol (2020)

Prevalence, Specificity and Determinants of Lipid-Interacting PDZ Domains from an In-Cell Screen and In Vitro Binding Experiments

af Ivarsson, Ylva, Wawrzyniak, Anna Maria, Kashyap, Rudra, Polanowska, Jolanta, Betzi, Stéphane, Lembo, Frédérique, Vermeiren, Elke, Chiheb, Driss, Lenfant, Nicolas, Morelli, Xavier, Borg, Jean-Paul, Reboul, Jérôme, Zimmermann, Pascale
Udgivet 2013

Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes

af Bouvet, Mickaël, Lugari, Adrien, Posthuma, Clara C., Zevenhoven, Jessika C., Bernard, Stéphanie, Betzi, Stéphane, Imbert, Isabelle, Canard, Bruno, Guillemot, Jean-Claude, Lécine, Patrick, Pfefferle, Susanne, Drosten, Christian, Snijder, Eric J., Decroly, Etienne, Morelli, Xavier
Udgivet 2014

Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases

af Schonbrunn, Ernst, Betzi, Stephane, Alam, Riazul, Martin, Mathew P., Becker, Andreas, Han, Huijong, Francis, Rawle, Chakrasali, Ramappa, Jakkaraj, Sudhakar, Kazi, Aslamuzzaman, Sebti, Said M., Cubitt, Christopher L., Gebhard, Anthony W., Hazlehurst, Lori A., Tash, Joseph S., Georg, Gunda I.
Udgivet 2013

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology

af Hammam, Kahina, Saez-Ayala, Magali, Rebuffet, Etienne, Gros, Laurent, Lopez, Sophie, Hajem, Berengere, Humbert, Martine, Baudelet, Emilie, Audebert, Stephane, Betzi, Stephane, Lugari, Adrien, Combes, Sebastien, Letard, Sebastien, Casteran, Nathalie, Mansfield, Colin, Moussy, Alain, De Sepulveda, Paulo, Morelli, Xavier, Dubreuil, Patrice
Udgivet i Nat Commun (2017)

Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis

af Cartier-Michaud, Amandine, Bailly, Anne-Laure, Betzi, Stéphane, Shi, Xiaoli, Lissitzky, Jean-Claude, Zarubica, Ana, Sergé, Arnauld, Roche, Philippe, Lugari, Adrien, Hamon, Véronique, Bardin, Florence, Derviaux, Carine, Lembo, Frédérique, Audebert, Stéphane, Marchetto, Sylvie, Durand, Bénédicte, Borg, Jean-Paul, Shi, Ning, Morelli, Xavier, Aurrand-Lions, Michel
Udgivet i PLoS Genet (2017)