Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer

The Cop9 signalosome complex (CSN) regulates the functional cycle of the major E3 ubiquitin ligase family, the cullin RING E3 ubiquitin ligases (CRLs). Activated CRLs are covalently modified by the ubiquitin-like protein Nedd8 (neural precursor cell expressed developmentally down-regulated protein 8...

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Bibliographic Details
Main Authors: Birol, Melissa, Enchev, Radoslav Ivanov, Padilla, André, Stengel, Florian, Aebersold, Ruedi, Betzi, Stéphane, Yang, Yinshan, Hoh, François, Peter, Matthias, Dumas, Christian, Echalier, Aude
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140821/
https://ncbi.nlm.nih.gov/pubmed/25144743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105688
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