Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer

The Cop9 signalosome complex (CSN) regulates the functional cycle of the major E3 ubiquitin ligase family, the cullin RING E3 ubiquitin ligases (CRLs). Activated CRLs are covalently modified by the ubiquitin-like protein Nedd8 (neural precursor cell expressed developmentally down-regulated protein 8...

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Detalhes bibliográficos
Main Authors: Birol, Melissa, Enchev, Radoslav Ivanov, Padilla, André, Stengel, Florian, Aebersold, Ruedi, Betzi, Stéphane, Yang, Yinshan, Hoh, François, Peter, Matthias, Dumas, Christian, Echalier, Aude
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140821/
https://ncbi.nlm.nih.gov/pubmed/25144743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105688
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