Prevalence, Specificity and Determinants of Lipid-Interacting PDZ Domains from an In-Cell Screen and In Vitro Binding Experiments

BACKGROUND: PDZ domains are highly abundant protein-protein interaction modules involved in the wiring of protein networks. Emerging evidence indicates that some PDZ domains also interact with phosphoinositides (PtdInsPs), important regulators of cell polarization and signaling. Yet our knowledge on...

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Detalhes bibliográficos
Main Authors: Ivarsson, Ylva, Wawrzyniak, Anna Maria, Kashyap, Rudra, Polanowska, Jolanta, Betzi, Stéphane, Lembo, Frédérique, Vermeiren, Elke, Chiheb, Driss, Lenfant, Nicolas, Morelli, Xavier, Borg, Jean-Paul, Reboul, Jérôme, Zimmermann, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563628/
https://ncbi.nlm.nih.gov/pubmed/23390500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054581
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