Prevalence, Specificity and Determinants of Lipid-Interacting PDZ Domains from an In-Cell Screen and In Vitro Binding Experiments

BACKGROUND: PDZ domains are highly abundant protein-protein interaction modules involved in the wiring of protein networks. Emerging evidence indicates that some PDZ domains also interact with phosphoinositides (PtdInsPs), important regulators of cell polarization and signaling. Yet our knowledge on...

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Bibliographic Details
Main Authors: Ivarsson, Ylva, Wawrzyniak, Anna Maria, Kashyap, Rudra, Polanowska, Jolanta, Betzi, Stéphane, Lembo, Frédérique, Vermeiren, Elke, Chiheb, Driss, Lenfant, Nicolas, Morelli, Xavier, Borg, Jean-Paul, Reboul, Jérôme, Zimmermann, Pascale
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563628/
https://ncbi.nlm.nih.gov/pubmed/23390500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054581
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