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Frizzled 7 and PIP(2) binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling
PDZ domain-containing proteins work as intracellular scaffolds to control spatio-temporal aspects of cell signalling. This function is supported by the ability of their PDZ domains to bind other proteins such as receptors, but also phosphoinositide lipids important for membrane trafficking. Here we...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5515355/ https://ncbi.nlm.nih.gov/pubmed/27386966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12101 |
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