A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding

BACKGROUND: Proteins may evolve through the recruitment and modification of discrete domains, and in many cases, protein action can be dissected at the domain level. PDZ domains are found in many important structural and signaling complexes, and are generally thought to interact with their protein p...

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Hlavní autoři: Lenfant, Nicolas, Polanowska, Jolanta, Bamps, Sophie, Omi, Shizue, Borg, Jean-Paul, Reboul, Jérôme
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091786/
https://ncbi.nlm.nih.gov/pubmed/21110867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-671
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