Protein–protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein

Protein–protein recognition is the cornerstone of multiple cellular and pathological functions. Therefore, protein–protein interaction inhibition (2P2I) is endowed with great therapeutic potential despite the initial belief that 2P2I was refractory to small-molecule intervention. Improved knowledge...

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Библиографические подробности
Главные авторы: Betzi, Stéphane, Restouin, Audrey, Opi, Sandrine, Arold, Stefan T., Parrot, Isabelle, Guerlesquin, Françoise, Morelli, Xavier, Collette, Yves
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2007
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148277/
https://ncbi.nlm.nih.gov/pubmed/18042718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707130104
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