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Protein–protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein

Protein–protein recognition is the cornerstone of multiple cellular and pathological functions. Therefore, protein–protein interaction inhibition (2P2I) is endowed with great therapeutic potential despite the initial belief that 2P2I was refractory to small-molecule intervention. Improved knowledge...

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Detalhes bibliográficos
Main Authors: Betzi, Stéphane, Restouin, Audrey, Opi, Sandrine, Arold, Stefan T., Parrot, Isabelle, Guerlesquin, Françoise, Morelli, Xavier, Collette, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148277/
https://ncbi.nlm.nih.gov/pubmed/18042718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707130104
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