Megatrends in bile acid receptor research

Por Adorini, Luciano, Schoonjans, Kristina, Friedman, Scott L.
Publicado no Hepatol Commun (2017)

Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model

Por Anfuso, Beatrice, Tiribelli, Claudio, Adorini, Luciano, Rosso, Natalia
Publicado no Sci Rep (2020)

Human Immunodeficiency Virus Type 1 gp120 and Other Activation Stimuli Are Highly Effective in Triggering Alpha Interferon and CC Chemokine Production in Circulating Plasmacytoid b...

Por Del Cornò, Manuela, Gauzzi, Maria Cristina, Penna, Giuseppe, Belardelli, Filippo, Adorini, Luciano, Gessani, Sandra
Publicado em 2005

Endogenous Interleukin-12 Is Critical for Controlling the Late but Not the Early Stage of Leishmania mexicana Infection in C57BL/6 Mice

Por Aguilar Torrentera, Fabiola, Laman, Jon D., Van Meurs, Marjan, Adorini, Luciano, Muraille, Eric, Carlier, Y.
Publicado em 2002

A dual agonist of farnesoid X receptor (FXR) and the G protein–coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice

Por Wang, Xiaoxin X., Luo, Yuhuan, Wang, Dong, Adorini, Luciano, Pruzanski, Mark, Dobrinskikh, Evgenia, Levi, Moshe
Publicado no J Biol Chem (2017)

FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice

Por Iracheta‐Vellve, Arvin, Calenda, Charles D., Petrasek, Jan, Ambade, Aditya, Kodys, Karen, Adorini, Luciano, Szabo, Gyongyi
Publicado no Hepatol Commun (2018)

Calcitriol derivatives with two different side-chains at C-20. Part 4: Further chain modifications that alter VDR-dependent monocytic differentiation potency in human leukemia cell...

Por Garay, Edward, Jankowski, Pawel, Lizano, Paulo, Marczak, Stanislaw, Maehr, Hubert, Adorini, Luciano, Uskokovic, Milan R., Studzinski, George P.
Publicado em 2007

The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury

Por Ferrigno, Andrea, Di Pasqua, Laura Giuseppina, Berardo, Clarissa, Siciliano, Veronica, Rizzo, Vittoria, Adorini, Luciano, Richelmi, Plinio, Vairetti, Mariapia
Publicado no PLoS One (2018)

Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

Por Winzler, Claudia, Rovere, Patrizia, Rescigno, Maria, Granucci, Francesca, Penna, Giuseppe, Adorini, Luciano, Zimmermann, Valerie S., Davoust, Jean, Ricciardi-Castagnoli, Paola
Publicado em 1997

Hepatic Carboxylesterase 1 Is Essential for Both Normal and Farnesoid X Receptor-Controlled Lipid Homeostasis

Por Xu, Jiesi, Li, Yuanyuan, Chen, Wei-Dong, Xu, Yang, Yin, Liya, Ge, Xuemei, Jadhav, Kavita, Adorini, Luciano, Zhang, Yanqiao
Publicado em 2014

TGR5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure-induced stress in mice

Por Eblimit, Zeena, Thevananther, Sundararajah, Karpen, Saul J., Taegtmeyer, Heinrich, Moore, David D., Adorini, Luciano, Penny, Daniel J., Desai, Moreshwar S.
Publicado no Cardiovasc Ther (2018)

A Peptide-binding Motif for I-A(g7), the Class II Major Histocompatibility Complex (MHC) Molecule of NOD and Biozzi AB/H Mice

Por Harrison, Leonard C., Honeyman, Margo C., Trembleau, Sylvie, Gregori, Silvia, Gallazzi, Fabio, Augstein, Petra, Brusic, Vladimir, Hammer, Juergen, Adorini, Luciano
Publicado em 1997

FXR Activation Increases Reverse Cholesterol Transport by Modulating Bile Acid Composition and Cholesterol Absorption

Por Xu, Yang, Li, Fei, Zalzala, Munaf, Xu, Jiesi, Gonzalez, Frank J, Adorini, Luciano, Lee, Yoon-Kwang, Yin, Liya, Zhang, Yanqiao
Publicado no Hepatology (2016)

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

Por Martinez, Nathan R., Augstein, Petra, Moustakas, Antonis K., Papadopoulos, George K., Gregori, Silvia, Adorini, Luciano, Jackson, David C., Harrison, Leonard C.
Publicado em 2003

Avicholic Acid: A Lead Compound from Birds on the Route to Potent TGR5 Modulators

Por Pellicciari, Roberto, Gioiello, Antimo, Sabbatini, Paola, Venturoni, Francesco, Nuti, Roberto, Colliva, Carolina, Rizzo, Giovanni, Adorini, Luciano, Pruzanski, Mark, Roda, Aldo, Macchiarulo, Antonio
Publicado em 2012

Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH

Por Baandrup Kristiansen, Maria Nicoline, Veidal, Sanne Skovgård, Christoffersen, Christina, Feigh, Michael, Vrang, Niels, Roth, Jonathan David, Erickson, Mary, Adorini, Luciano, Jelsing, Jacob
Publicado no BMC Gastroenterol (2019)

Obeticholic acid reduces biliary and hepatic matrix metalloproteinases activity in rat hepatic ischemia/reperfusion injury

Por Ferrigno, Andrea, Palladini, Giuseppina, Di Pasqua, Laura Giuseppina, Berardo, Clarissa, Richelmi, Plinio, Cadamuro, Massimiliano, Fabris, Luca, Perlini, Stefano, Adorini, Luciano, Vairetti, Mariapia
Publicado no PLoS One (2020)

The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria

Por Wang, Xiaoxin X., Jiang, Tao, Shen, Yan, Adorini, Luciano, Pruzanski, Mark, Gonzalez, Frank J., Scherzer, Pnina, Lewis, Linda, Miyazaki-Anzai, Shinobu, Levi, Moshe
Publicado em 2009

Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR

Por Jadhav, Kavita, Xu, Yang, Xu, Yanyong, Li, Yuanyuan, Xu, Jiesi, Zhu, Yingdong, Adorini, Luciano, Lee, Yoon Kwang, Kasumov, Takhar, Yin, Liya, Zhang, Yanqiao
Publicado no Mol Metab (2018)

Calcitriol Suppresses Antiretinal Autoimmunity through Inhibitory Effects on the Th17 Effector Response

Por Tang, Jun, Zhou, Ru, Luger, Dror, Zhu, Wei, Silver, Phyllis B., Grajewski, Rafael S., Su, Shao-Bo, Chan, Chi-Chao, Adorini, Luciano, Caspi, Rachel R.
Publicado em 2009