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Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model
Pharmacological treatments for non-alcoholic steatohepatitis (NASH) are still unsatisfactory. Fibrosis is the most significant predictor of mortality and many anti-fibrotic agents are under evaluation. Herein, we assessed in vitro the effects of the FXR agonist obeticholic acid (OCA) and the dual FX...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6997404/ https://ncbi.nlm.nih.gov/pubmed/32015483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58562-x |
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