Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH

BACKGROUND: Compounds in clinical development for nonalcoholic steatohepatitis (NASH) improve liver histopathology in diet-induced obese mouse models of biopsy-confirmed NASH. Since the biopsy section used for histopathological evaluation represents only < 1% of the whole mouse liver, we evaluate...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMC Gastroenterol
Hauptverfasser: Baandrup Kristiansen, Maria Nicoline, Veidal, Sanne Skovgård, Christoffersen, Christina, Feigh, Michael, Vrang, Niels, Roth, Jonathan David, Erickson, Mary, Adorini, Luciano, Jelsing, Jacob
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935483/
https://ncbi.nlm.nih.gov/pubmed/31883514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-019-1149-z
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge