Hepatic Carboxylesterase 1 Is Essential for Both Normal and Farnesoid X Receptor-Controlled Lipid Homeostasis

Non-alcoholic fatty liver disease (NAFLD) is one of the major health concerns worldwide. Farnesoid X receptor (FXR) is considered a therapeutic target for treatment of NAFLD. However, the mechanism by which activation of FXR lowers hepatic triglyceride (TG) levels remains unknown. Here we investigat...

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Detalhes bibliográficos
Main Authors: Xu, Jiesi, Li, Yuanyuan, Chen, Wei-Dong, Xu, Yang, Yin, Liya, Ge, Xuemei, Jadhav, Kavita, Adorini, Luciano, Zhang, Yanqiao
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938573/
https://ncbi.nlm.nih.gov/pubmed/24038130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26714
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