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Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR

OBJECTIVES: Activation of the bile acid (BA) receptors farnesoid X receptor (FXR) or G protein-coupled bile acid receptor (GPBAR1; TGR5) improves metabolic homeostasis. In this study, we aim to determine the impact of pharmacological activation of bile acid receptors by INT-767 on reversal of diet-i...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Jadhav, Kavita, Xu, Yang, Xu, Yanyong, Li, Yuanyuan, Xu, Jiesi, Zhu, Yingdong, Adorini, Luciano, Lee, Yoon Kwang, Kasumov, Takhar, Yin, Liya, Zhang, Yanqiao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870099/
https://ncbi.nlm.nih.gov/pubmed/29361497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.01.005
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