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Hepatic forkhead box protein A3 regulates ApoA-I expression, cholesterol efflux and atherogenesis
OBJECTIVE: To determine the role of hepatic forkhead box A3 (FOXA3) in lipid metabolism and atherosclerosis. APPROACH AND RESULTS: Hepatic FOXA3 expression was reduced in diabetic or high fat diet-fed mice or patients with nonalcoholic steatohepatitis. We then used adenoviruses to over-express or kn...
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| Udgivet i: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6656627/ https://ncbi.nlm.nih.gov/pubmed/31291759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312610 |
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