Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis

Macrophages play a crucial role in the pathogenesis of atherosclerosis, but the molecular mechanisms remain poorly understood. Here we show that microRNA-34a (miR-34a) is a key regulator of macrophage cholesterol efflux and reverse cholesterol transport by modulating ATP-binding cassette transporter...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Xu, Yanyong, Xu, Yang, Zhu, Yingdong, Sun, Huihui, Juguilon, Cody, Li, Feng, Fan, Daping, Yin, Liya, Zhang, Yanqiao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6952168/
https://ncbi.nlm.nih.gov/pubmed/31604677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.09.008
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