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Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and is Enhanced by Anti-miR33 in Atherosclerosis

RATIONALE: Therapeutically targeting macrophage reverse cholesterol transport is a promising approach to treat atherosclerosis. Macrophage energy metabolism can significantly influence macrophage phenotype, but how this is controlled in foam cells is not known. Bioinformatic pathway analysis predict...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Karunakaran, Denuja, Thrush, A. Brianne, Nguygen, My-Anh, Richards, Laura, Geoffrion, Michele, Singaravelu, Ragunath, Ramphos, Eleni, Shangari, Prakriti, Ouimet, Mireille, Pezacki, John P, Moore, Kathryn J, Perisic, Ljubica, Maegdefessel, Lars, Hedin, Ulf, Harper, Mary-Ellen, Rayner, Katey J
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578799/
https://ncbi.nlm.nih.gov/pubmed/26002865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.305624
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