Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

Atherosclerosis results from maladaptive inflammation driven primarily by macrophages, whose recruitment and proliferation drive plaque progression. In advanced plaques, macrophage death contributes centrally to the formation of plaque necrosis, which underlies the instability that promotes plaque r...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Karunakaran, Denuja, Geoffrion, Michele, Wei, Lihui, Gan, Wei, Richards, Laura, Shangari, Prakriti, DeKemp, Ella M., Beanlands, Rachelle A., Perisic, Ljubica, Maegdefessel, Lars, Hedin, Ulf, Sad, Subash, Guo, Liang, Kolodgie, Frank D., Virmani, Renu, Ruddy, Terrence, Rayner, Katey J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985228/
https://ncbi.nlm.nih.gov/pubmed/27532042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600224
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