Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

Atherosclerosis results from maladaptive inflammation driven primarily by macrophages, whose recruitment and proliferation drive plaque progression. In advanced plaques, macrophage death contributes centrally to the formation of plaque necrosis, which underlies the instability that promotes plaque r...

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發表在:Sci Adv
Main Authors: Karunakaran, Denuja, Geoffrion, Michele, Wei, Lihui, Gan, Wei, Richards, Laura, Shangari, Prakriti, DeKemp, Ella M., Beanlands, Rachelle A., Perisic, Ljubica, Maegdefessel, Lars, Hedin, Ulf, Sad, Subash, Guo, Liang, Kolodgie, Frank D., Virmani, Renu, Ruddy, Terrence, Rayner, Katey J.
格式: Artigo
語言:Inglês
出版: American Association for the Advancement of Science 2016
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985228/
https://ncbi.nlm.nih.gov/pubmed/27532042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600224
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