Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

Atherosclerosis results from maladaptive inflammation driven primarily by macrophages, whose recruitment and proliferation drive plaque progression. In advanced plaques, macrophage death contributes centrally to the formation of plaque necrosis, which underlies the instability that promotes plaque r...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Karunakaran, Denuja, Geoffrion, Michele, Wei, Lihui, Gan, Wei, Richards, Laura, Shangari, Prakriti, DeKemp, Ella M., Beanlands, Rachelle A., Perisic, Ljubica, Maegdefessel, Lars, Hedin, Ulf, Sad, Subash, Guo, Liang, Kolodgie, Frank D., Virmani, Renu, Ruddy, Terrence, Rayner, Katey J.
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985228/
https://ncbi.nlm.nih.gov/pubmed/27532042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600224
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