miRNA Targeting of Oxysterol Binding Protein-like 6 (OSBPL6) Regulates Cholesterol Trafficking and Efflux

OBJECTIVE: Cholesterol homeostasis is fundamental to human health, and is thus, tightly regulated. MicroRNAs exert potent effects on biological pathways, including cholesterol metabolism, by repressing genes with related functions. We reasoned that this mode of pathway regulation could be exploited...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Ouimet, Mireille, Hennessy, Elizabeth J., van Solingen, Coen, Koelwyn, Graeme J., Hussein, Maryem A., Ramkhelawon, Bhama, Rayner, Katey J., Temel, Ryan E., Perisic, Ljubica, Hedin, Ulf, Maegdefessel, Lars, Garabedian, Michael J., Holdt, Lesca M., Teupser, Daniel, Moore, Kathryn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850101/
https://ncbi.nlm.nih.gov/pubmed/26941018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307282
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