miRNA Targeting of Oxysterol Binding Protein-like 6 (OSBPL6) Regulates Cholesterol Trafficking and Efflux

OBJECTIVE: Cholesterol homeostasis is fundamental to human health, and is thus, tightly regulated. MicroRNAs exert potent effects on biological pathways, including cholesterol metabolism, by repressing genes with related functions. We reasoned that this mode of pathway regulation could be exploited...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Ouimet, Mireille, Hennessy, Elizabeth J., van Solingen, Coen, Koelwyn, Graeme J., Hussein, Maryem A., Ramkhelawon, Bhama, Rayner, Katey J., Temel, Ryan E., Perisic, Ljubica, Hedin, Ulf, Maegdefessel, Lars, Garabedian, Michael J., Holdt, Lesca M., Teupser, Daniel, Moore, Kathryn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850101/
https://ncbi.nlm.nih.gov/pubmed/26941018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307282
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