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The long noncoding RNA CHROME regulates cholesterol homeostasis in primate

The human genome encodes thousands of long non-coding RNAs (lncRNAs), the majority of which are poorly conserved and uncharacterized. Here we identify a primate-specific lncRNA (CHROME), elevated in the plasma and atherosclerotic plaques of individuals with coronary artery disease, that regulates ce...

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Detalhes bibliográficos
Publicado no:Nat Metab
Main Authors: Hennessy, Elizabeth J., van Solingen, Coen, Scacalossi, Kaitlyn R., Ouimet, Mireille, Afonso, Milessa S., Prins, Jurrien, Koelwyn, Graeme J., Sharma, Monika, Ramkhelawon, Bhama, Carpenter, Susan, Busch, Albert, Chernogubova, Ekaterina, Matic, Ljubica Perisic, Hedin, Ulf, Maegdefessel, Lars, Caffrey, Brian E., Hussein, Maryem A., Ricci, Emiliano P., Temel, Ryan E., Garabedian, Michael J., Berger, Jeffrey S., Vickers, Kasey C., Kanke, Matthew, Sethupathy, Praveen, Teupser, Daniel, Holdt, Lesca M., Moore, Kathryn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691505/
https://ncbi.nlm.nih.gov/pubmed/31410392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-018-0004-9
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