miRNA Targeting of Oxysterol Binding Protein-like 6 (OSBPL6) Regulates Cholesterol Trafficking and Efflux

OBJECTIVE: Cholesterol homeostasis is fundamental to human health, and is thus, tightly regulated. MicroRNAs exert potent effects on biological pathways, including cholesterol metabolism, by repressing genes with related functions. We reasoned that this mode of pathway regulation could be exploited...

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Опубликовано в: :Arterioscler Thromb Vasc Biol
Главные авторы: Ouimet, Mireille, Hennessy, Elizabeth J., van Solingen, Coen, Koelwyn, Graeme J., Hussein, Maryem A., Ramkhelawon, Bhama, Rayner, Katey J., Temel, Ryan E., Perisic, Ljubica, Hedin, Ulf, Maegdefessel, Lars, Garabedian, Michael J., Holdt, Lesca M., Teupser, Daniel, Moore, Kathryn J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850101/
https://ncbi.nlm.nih.gov/pubmed/26941018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307282
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