miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages

Liver X receptors (LXRα and LXRβ) are key transcription factors in cholesterol metabolism that regulate cholesterol biosynthesis/efflux and bile acid metabolism/excretion in the liver and numerous organs. In macrophages, LXR signaling modulates cholesterol handling and the inflammatory response, pat...

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Bibliografiske detaljer
Main Authors: Vinod, Manjula, Chennamsetty, Indumathi, Colin, Sophie, Belloy, Loic, De Paoli, Federica, Schaider, Helmut, Graier, Wolfgang F., Frank, Saša, Kratky, Dagmar, Staels, Bart, Chinetti-Gbaguidi, Giulia, Kostner, Gerhard M.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Pub. Co 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996726/
https://ncbi.nlm.nih.gov/pubmed/24603323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.02.006
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