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Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice
Elevated plasma lipoprotein(a) (LPA) levels are recognized as an independent risk factor for cardiovascular diseases. Our knowledge on LPA metabolism is incomplete, which makes it difficult to develop LPA-lowering medications. Nicotinic acid (NA) is the main drug recommended for the treatment of pat...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466008/ https://ncbi.nlm.nih.gov/pubmed/22930813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M029769 |
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