Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice

Elevated plasma lipoprotein(a) (LPA) levels are recognized as an independent risk factor for cardiovascular diseases. Our knowledge on LPA metabolism is incomplete, which makes it difficult to develop LPA-lowering medications. Nicotinic acid (NA) is the main drug recommended for the treatment of pat...

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Bibliographische Detailangaben
Hauptverfasser: Chennamsetty, Indumathi, Kostner, Karam M., Claudel, Thierry, Vinod, Manjula, Frank, Sasa, Weiss, Thomas S., Trauner, Michael, Kostner, Gerhard M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466008/
https://ncbi.nlm.nih.gov/pubmed/22930813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M029769
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