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Calcitriol Suppresses Antiretinal Autoimmunity through Inhibitory Effects on the Th17 Effector Response

Experimental autoimmune uveitis (EAU) serves as a model for human autoimmune uveitis and for cell-mediated autoimmunity in general. EAU induced in mice by immunization with the retinal Ag interphotoreceptor retinoid-binding protein in CFA is driven by the Th17 response. Oral calcitriol (1,25-dihydro...

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Detalhes bibliográficos
Main Authors: Tang, Jun, Zhou, Ru, Luger, Dror, Zhu, Wei, Silver, Phyllis B., Grajewski, Rafael S., Su, Shao-Bo, Chan, Chi-Chao, Adorini, Luciano, Caspi, Rachel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756755/
https://ncbi.nlm.nih.gov/pubmed/19342637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801543
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