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Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category
Experimental autoimmune uveitis (EAU) represents autoimmune uveitis in humans. We examined the role of the interleukin (IL)-23–IL-17 and IL-12–T helper cell (Th)1 pathways in the pathogenesis of EAU. IL–23 but not IL-12 was necessary to elicit disease by immunization with the retinal antigen (Ag) in...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292220/ https://ncbi.nlm.nih.gov/pubmed/18391061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071258 |
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