AS101 ameliorates experimental autoimmune uveitis by regulating Th1 and Th17 responses and inducing Treg cells

AS101 is an organotellurium compound with multifaceted immunoregulatory properties that is remarkable for its lack of toxicity. We tested the therapeutic effect of AS101 in experimental autoimmune uveitis (EAU), a model for human autoimmune uveitis. Unexpectedly, treatment with AS101 elicited Treg g...

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Bibliografiske detaljer
Udgivet i:J Autoimmun
Main Authors: Bing, So Jin, Shemesh, Itay, Chong, Wai Po, Horai, Reiko, Jittayasothorn, Yingyos, Silver, Phyllis B., Sredni, Benjamin, Caspi, Rachel R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6513711/
https://ncbi.nlm.nih.gov/pubmed/30853312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2019.02.006
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