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Autoimmunity to neuroretina in the concurrent absence of IFN-γ and IL-17A is mediated by a GM-CSF-driven eosinophilic inflammation
IFN-γ and IL-17A can each elicit ocular autoimmunity independently of the other. Since absence of IFN-γ or IL-17A individually failed to abolish pathology of experimental autoimmune uveitis (EAU), we examined EAU development in the absence of both these cytokines. Ifng(−/−)Il17a(−/−) mice were fully...
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| Udgivet i: | J Autoimmun |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7572578/ https://ncbi.nlm.nih.gov/pubmed/32593472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2020.102507 |
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