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Retina-specific T regulatory cells bring about resolution and maintain remission of autoimmune uveitis

Experimental autoimmune uveitis (EAU) induced in mice by immunization with the retinal antigen IRBP is a model of human autoimmune uveitis. We examined whether T regulatory (Treg) cells found in uveitic eyes are (i) IRBP specific, (ii) functionally suppressive, and (iii) play a role in natural resol...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Silver, Phyllis, Horai, Reiko, Chen, Jun, Jittayasothorn, Yingyos, Chan, Chi-Chao, Villasmil, Rafael, Kesen, Muge R., Caspi, Rachel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459505/
https://ncbi.nlm.nih.gov/pubmed/25716996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402650
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