IL-27p28 inhibits central nervous system autoimmunity by concurrently antagonizing Th1 and Th17 responses

Central nervous system (CNS) autoimmunity such as uveitis and multiple sclerosis is accompanied by Th1 and Th17 responses. In their corresponding animal models, experimental autoimmune uveitis (EAU) and experimental autoimmune encephalomyelitis (EAE), both responses are induced and can drive disease...

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Autori principali: Chong, Wai Po, Horai, Reiko, Mattapallil, Mary J., Silver, Phyllis B., Chen, Jun, Zhou, Ru, Sergeev, Yuri, Villasmil, Rafael, Chan, Chi-Chao, Caspi, Rachel R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975693/
https://ncbi.nlm.nih.gov/pubmed/24021664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.08.003
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